Nephrotic syndrome is a group of clinical manifestations of glomerular disease, not an independent disease, a large number of proteinuria is a characteristic of nephrotic syndrome, due to glomerular capillary filtration membrane damage occurred. It may be primary nephrotic syndrome, may also be secondary to nephrotic syndrome. Most adults and children with nephrotic syndrome as primary, secondary nephrotic syndrome in China due to systemic lupus erythematosus, allergic purpura, diabetes is the most common.
Children with nephrotic syndrome is characterized by "three high and one low" that is highly swollen, highly proteinuria, hypercholesterolemia and hypoproteinemia. Symptoms of nephrotic syndrome are often an important aspect of pre-nephrotic syndrome patients. Nephrotic syndrome symptoms than other symptoms of kidney disease to be obvious, easily found by patients. In addition to routine examination found that kidney disease, nephrotic syndrome and which should pay attention to it, experts say to understand the symptoms of nephrotic syndrome, careful observation of their own physical changes is an important aspect of the discovery of nephrotic syndrome.
Whole body edema, nephrotic syndrome is the most significant symptoms. The presence of edema and its severity was positively correlated with the extent of hypoproteinemia. Known as renal edema, due to a large number of proteinuria caused by low plasma protein. Another reason is the decline in glomerular filtration, and renal tubular reabsorption of water and sodium is still good, resulting in water and sodium retention flow, tissue gap in the retention of water, light eyelid and facial edema, severe systemic edema or there is pleural effusion, ascites. Mainly seen in nephritis edema. Almost all patients with nephrotic syndrome will be varying degrees of edema, edema can be sustained for several weeks or months, or in the whole course of time swollen. Infection, often so that swelling or relapse, or even azotemia. At this time often show anorexia, nausea, vomiting, abdominal distension and other symptoms of gastrointestinal disorders.
Severe edema such as nephrotic syndrome patients with lower limbs or systemic edema, persistent refractory, will seriously affect the work and life. Get rid of nephrotic syndrome, can not blindly go with the lifting of edema. The key is to repair damaged glomerular innate cells that can radically eliminate edema.
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