Henoch-Schonlein purpura is a common capillary allergic disease, the main pathological basis for a wide range of capillary inflammation, purpura skin, gastrointestinal mucosal bleeding, joint swelling and pain and nephritis and other symptoms as the main clinical manifestations, a small number of patients also accompanied by blood vessels neurogenic edema.
What are the symptoms of allergic purpura?
1 Purpura skin: more common in the limbs and buttocks, symmetrical distribution, stretch side more, appear in batches, less in face and trunk. From the beginning purple purplish rash, higher than the leather, don’t fade under pressure, a few days later turned to dark purple, the final was brown and faded. A small number of severe purpura in children may be integrated into bullae with hemorrhagic necrosis, some cases may be associated with urticaria and angioneurotic edema. Skin purpura usually subsides after 4 to 6 weeks, some children relapse after a few weeks interval, a few months later.
2 Gastrointestinal symptoms: generally severe paroxysmal abdominal pain, often located in the umbilical or lower abdomen may be associated with vomiting, but rarely hematemesis, some children may have melena or bloody stools, sometimes complicated by intussusception, Intestinal obstruction or intestinal perforation who.
3 Joint symptoms: about 1/3 of the cases can occur knee, ankle, elbow, wrist and other large joint swelling and pain, limited mobility.
4 Kidney symptoms: 30% to 60% of cases have clinical manifestations of kidney damage. Kidney symptoms occur within 1 month of onset, but also later in the course of the disease, after the disappearance of other symptoms occur, the majority of children with hematuria, proteinuria and tubular urine, with increased blood pressure and edema, a purpuric nephritis, a few showed nephrotic syndrome.
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