How can renal failure be prevented in patients with IgA nephropathy?

Primary IgA nephropathy is one of the most common glomerular diseases in clinical practice. It is characterized by repeated attacks of macroscopic hematuria or microscopic hematuria, accompanied by varying degrees of proteinuria, impairment of renal function and deposition of immunoglobulin IgA in renal tissue.

IgA nephropathy is insidious, more common in young and middle-aged, and its clinical manifestations are perse and complex. Some patients with symptoms are not obvious, the condition can be stable for many years, does not occur renal failure. Some patients, however, develop rapidly and progress to end-stage renal failure within 3-5 years of onset. So how can IgA nephropathy prevent or delay the occurrence of chronic renal failure?

1, first of all, we should make clear the type and severity of pathological damage

IgA nephropathy usually requires a renal biopsy to make a definitive diagnosis. If the pathology prompted glomerulosclerosis, tubular atrophy, interstitial inflammation and fibrosis, vascular sclerosis, chronic disease often prompts the obvious, is inevitable to develop end-stage renal failure. If the pathology showed mesangial proliferation obviously, cellular crescents, vasculitis is changed, tubulointerstitial inflammatory cell infiltration, suggesting that disease activity, need active treatment, to prevent the progression of renal disease, save renal function.

2, we should pay attention to proteinuria and hypertension treatment

Many patients with IgA nephropathy exhibit marked proteinuria (urine routine, 2+ above, 24 hours urine protein, more than 1 grams), and even proteinuria within the nephrotic syndrome. Studies have shown that proteinuria is an important risk factor for the progression of kidney disease and poor prognosis, and should be treated actively. Similarly, hypertension is a common complication of IgA nephropathy and is one of the most important risk factors for the progression of kidney disease. Strict control of hypertension and proteinuria has almost decisive effect on the prognosis of patients with IgA nephropathy. Clinical experience has shown that renal failure deteriorates fastest in patients who fail to treat proteinuria and hypertension.

3, we should pay attention to regular follow-up of the disease

Whether hypertension or proteinuria treatment, need regular follow-up, under the close guidance of doctors, constantly adjust the medication program, in order to reduce or avoid side effects of drugs. Especially the use of immunosuppressant, and even more so, to beware of infection, such as during the treatment fever, cough and other symptoms, should be swift to kidney specialist examination, so as not to delay the disease.

4, avoid fatigue and abuse of drugs

Fatigue is also an important factor in the progression of kidney disease. Clinical often encounter some patients, after illness, do not take a good rest, work overtime, stay up late, travel, excessive entertainment and so on, leading to low resistance, rapid progress in disease. Rational drug treatment is necessary, but must be carried out under the guidance of specialist not hearsay, take secret recipe, cause of drug-induced renal damage.

5, have a reasonable diet

Normal renal function, only need a balanced diet, pay attention to food hygiene, eat more fresh fruits and vegetable dish, can fully complement protein. Renal dysfunction or hypertension patients should pay attention to low salt diet, according to the impairment of renal function, appropriate control of protein intake, regular examination of nutritional status, to avoid excessive nutrition and malnutrition occur.

Above is the relevant knowledge about the prevention of renal failure in patients with IGA nephropathy, and if you need a detailed understanding, or still do not understand, you can consult our online expert, our experts will giveyou reply as soon as possible.

How can renal failure be prevented in patients with IgA nephropathy?